Keratinization and papillary formation of the conjunctiva were found histologically in biopsy specimens from a child with the lamellar type of ichthyosis congenita. The changes are thought to be a manifestation of the systemic disease rather than a secondary phenomenon.
Katowitz JA, Yolles EA, Yanoff M. Ichthyosis Congenita. Arch Ophthalmol. 1974;91(3):208-210. doi:10.1001/archopht.1974.03900060216013