The presently reported case is the eighth in which a cornea subjected to implantation of a keratoprosthesis has subsequently been examined pathologically. Among the several well-recognized complications of prosthokeratoplasty illustrated here is epithelialization of the anterior chamber. Ingrowth of surface epithelium has been found in six of the seven previously reported cases, the epithelium having proliferated along a track formed between the keratoprosthesis and the adjacent corneal stroma.
Ferry AP, Gordon BL. Epithelialization of the Anterior ChamberA Complication of Prosthokeratoplasty. Arch Ophthalmol. 1974;91(4):281-284. doi:10.1001/archopht.1974.03900060291009