June 1974

Experimental Disciform Serous Retinal DetachmentII. Autoradiography of Photoreceptor Protein Metabolism

Author Affiliations

Boston and Baltimore
From the Howe Laboratory of Ophthalmology, Harvard University Medical School, Massachusetts Eye and Ear Infirmary, Boston, and the Wilmer Ophthalmological Institute, the Johns Hopkins University School of Medicine, Baltimore.

Arch Ophthalmol. 1974;91(6):481-483. doi:10.1001/archopht.1974.03900060495013

Protein metabolism of photoreceptor cells was studied by radioautography in disciform serous retinal detachments. The basic sequence of new protein synthesis and distribution within the visual cells was similar to that in control eyes with attached retinas. Compared to retinas with experimental rhegmatogenous detachments, the outer segment renewal process was relatively intact. This may be a consequence of a diffuse protein renewal process being maintained in serous but not in rhegmatogenous detachments.