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To the Editor.
—Regarding the article by Saunders, entitled "Congenital Sudoriferous Cyst of the Orbit" published in the Archives (89:205-206, 1973), I do not believe it necessary to invoke a sweat gland origin for the cyst described. A retention cyst originating from the lacrimal gland ductules also may be lined by a double layer of cuboidal epithelium and appear optically empty under the light microscope (see Duke-Elder, vol 8, pp 1137-1140). We have received two such specimens in the past year from adult patients with identical pathologic findings at the New York University Eye Pathology Laboratory. One was clearly attached to the principal accessory lacrimal gland superotemporally and the other simply formed a large cyst in the upper fornix. Figure 4 of Saunders article showing ectopic lacrimal gland tissue adjacent to the cyst wall lends further support to this hypothesis. These cysts may originate from Krause's glands and might also
Charles NC. Sudoriferous Cyst. Arch Ophthalmol. 1974;92(1):89. doi:10.1001/archopht.1974.01010010093020