Although the causative role of the retinal break in the onset of retinal detachment is well established, guidelines for the understanding of the relative risks of various types of breaks have been largely lacking because of the paucity of prospective clinical studies of retinal breaks. A series of 162 retinal breaks in 125 phakic, non-"fellow" eyes was observed without treatment for from three to nine years. None of the breaks progressed to clinical retinal detachment. One patient did develop a small subclinical retinal detach. ment. It was concluded that the presence or absence of symptoms in association with the onset of the retinal break is the most important prognostic criterion. Prophylactic treatment is rarely indicated in asymptomatic retinal breaks, but should be recommended in cases of symptomatic breaks.
Byer NE. Prognosis of Asymptomatic Retinal Breaks. Arch Ophthalmol. 1974;92(3):208-210. doi:10.1001/archopht.1974.01010010216005