Dexamethasone, 0.1%, was administered topically to rabbits three times daily at various intervals after they sustained central corneal wounds. The eyes treated during the first postoperative week demonstrated significantly diminished wound tensile strength compared to either the contralateral eyes or untreated controls. Eyes treated during the third postoperative week had no reduction in corneal wound tensile strength.
Sugar J, Chandler JW. Experimental Corneal Wound StrengthEffect of Topically Applied Corticosteroids. Arch Ophthalmol. 1974;92(3):248–249. doi:10.1001/archopht.1974.01010010256018