This report describes a patient with a meibomian gland carcinoma that presented clinically as a lacrimal gland tumor with only minimal involvement of the adjacent eyelids. There was metastatic involvement of a right preauricular lymph node. Initial biopsy examinations of both the lacrimal gland and the preauricular node revealed a poorly differentiated carcinoma, primary site undetermined. Orbital exenteration, however, revealed that the lesion was a multifocal sebaceous carcinoma involving both upper and lower eyelids.
Although meibomian gland carcinoma is not usually included in the differential diagnosis of tumors of the lacrimal gland, it should be considered when the clinician is confronted with a solid tumor in the fossa of the lacrimal gland.
Shields JA, Font RL. Meibomian Gland Carcinoma Presenting as a Lacrimal Gland Tumor. Arch Ophthalmol. 1974;92(4):304-306. doi:10.1001/archopht.1974.01010010314009