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January 1975

Ocular Involvement in Disseminated Intravascular Coagulopathy

Author Affiliations

From the Howe Laboratory of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston; and the Clinical Branch, National Eye Institute, Bethesda, Md.

Arch Ophthalmol. 1975;93(1):1-8. doi:10.1001/archopht.1975.01010020005001

Seven cases illustrate the ocular pathology of disseminated intravascular coagulopathy in its several stages, and correlate these changes with the clinical manifestations. The prime abnormalities consisted of detachments of the retina, vacuolar disruption of the pigment epithelium, choroidal hemorrhage, and, most importantly, thrombotic occlusion of the choriocapillaris and of the juxtaposed vessels in the submacular and peripapillary regions. The changes were characteristically symmetrical in the two eyes.