Microcystic corneal dystrophy was first described in 1964. Since then, several reports have elaborated on the original findings plus other associated corneal changes. The cause is unknown, but pathological studies have now been done in several cases. The corneal changes are subtle and easy to miss on routine examination.
This study of 17 patients was undertaken to further evaluate the signs and symptoms of this abnormality and to emphasize techniques of examination. Detailed clinical and laboratory evaluations of tear function were performed. No definite association between tear function and the corneal changes could be determined. In this group of patients, the process seemed benign with minimal symptoms.
Luxenberg MN, Friedland BR, Holder JM. Superficial Microcystic Corneal Dystrophy. Arch Ophthalmol. 1975;93(2):107-110. doi:10.1001/archopht.1975.01010020113002