A case of acrodermatitis enteropathica occurred with corneal changes consisting of linear subepithelial corneal opacities. From the results of histochemical and electronmicrographic studies on a biopsy specimen of the corneal lesion, no definite conclusion may be drawn as to whether the corneal changes are a manifestation of acrodermatitis enteropathica or a result of iodochlorhydroxyquin therapy.
Warshawsky RS, Hill CW, Doughman DJ, Harris JE. Acrodermatitis EnteropathicaCorneal Involvement With Histochemical and Electron Micrographic Studies. Arch Ophthalmol. 1975;93(3):194-197. doi:10.1001/archopht.1975.01010020202007