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September 1975

Ibuprofen and Visual FunctionProspective Evaluation

Author Affiliations

From the Department of Surgery (Ophthalmology) (Dr Melluish) and the Clinical Investigational Unit (Dr Brooks), Bronson Methodist Hospital, Kalamazoo, Mich; the Department of Family Practice, Borgess Hospital, Kalamazoo (Dr Ruoff); and the Hypersensitivity Diseases Research Unit (Mrs Cross) and the Experimental Medicine Unit (Mr Sanborn), the Upjohn Company.

Arch Ophthalmol. 1975;93(9):781-782. doi:10.1001/archopht.1975.01010020675003

• Eye evaluations before and after 24 weeks of treatment with either ibuprofen (Motrin) or aspirin did not show eye toxicity with either drug in a double-blind study of 78 patients with osteoarthritis. The possibility of eye complications resulting from ibuprofen therapy suggested in two earlier reports has not been confirmed in clinical usage in other countries or in clinical trials in the United States.