• A case of giant retinal tear treated by injection with dimethicone 350 (medical fluid silicone) was observed for six years before enucleation. About four months after the injection, signs of anterior segment ischemia were evident. A year after the injection, an injury resulted in displacement of dimethicone 350 into the anterior chamber. Enucleation was done because of pain.
Sugar HS, Okamura ID. Ocular Findings Six Years After Intravitreal Silicone Injection. Arch Ophthalmol. 1976;94(4):612-615. doi:10.1001/archopht.1976.03910030296009