• A possible systemic reaction to acetylcholine chloride injected into the anterior chamber of the eye occurred in a 65-year-old patient who had a cataract extraction while under general anesthesia. Following cataract extraction, 20 mg of acetylcholine chloride was injected into the anterior chamber of the eye. Immediately following injection, hypotension and bradycardia (48 beats per minute) occurred.
Babinski M, Smith RB, Wickerham EP. Hypotension and Bradycardia Following Intraocular Acetylcholine InjectionReport of a Case. Arch Ophthalmol. 1976;94(4):675-676. doi:10.1001/archopht.1976.03910030339018