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Article
August 1976

Malignant Melanoma of the Skin Metastatic to the EyeFrequency in Autopsy Series

Author Affiliations

From the Clinical Branch (Dr Fishman) and Laboratory of Vision Research (Dr Kuwabara), National Eye Institute, and the Laboratory of Pathology (Dr Tomaszewski), National Cancer Institute, National Institutes of Health, US Department of Health, Education and Welfare, Bethesda, Md.

Arch Ophthalmol. 1976;94(8):1309-1311. doi:10.1001/archopht.1976.03910040181010
Abstract

• Results of histopathologic examination of the eyes of 15 consecutive patients with metastatic malignant melanoma arising in the skin demonstrated evidence of intraocular metastasis in five patients. The metastases were microscopic, epithelioid, minimally pigmented, and occurred in both the choroid and the retina. All patients were asymptomatic. Those patients with ocular metastases all had primary malignant neoplasms of the superficial, spreading variety and associated central nervous system metastases.

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