• Case reports are presented of four corneal grafts that were replaced 7 to 26 days after the initial surgery. The reasons for regrafting were incomplete epithelialization of the donor cornea by the host, poor donor material, and ring synechiae with secondary glaucoma. All regrafts in these cases have remained transparent. The advantages of early regrafting include earlier visual rehabilitation, avoidance of host corneal vascularization, and prevention of fibrotic organization of synechiae when present. Despite the prevalent notion that early corneal regrafting is inadvisable, when faced with a corneal graft that has little chance of success and then only with prolonged and intensive treatment, we believe that early regrafting may be advisable.
Mondino BJ, Brown SI. Early Repeated Corneal Grafts. Arch Ophthalmol. 1976;94(10):1720-1722. doi:10.1001/archopht.1976.03910040494005