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February 1977

Retrolental FibroplasiaI. Clinical Observations

Author Affiliations

From the Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami (Fla) School of Medicine.

Arch Ophthalmol. 1977;95(2):217-223. doi:10.1001/archopht.1977.04450020019002

• The changes occurring in retrolental fibroplasia were studied in 97 premature infants with fundus photography and fluorescein angiography. The macrovascular lesion of proliferative retrolental fibroplasia was identified as a functioning arteriovenous shunt. The microvascular abnormalities were capillary tufts, collaterals, capillary-free zones, and neovascular membranes. Regression was signaled by the ingrowth of capillaries from the shunt into the avascular retina. Cicatrization was characterized by persistence of the vascular abnormalities of the prollferative phase and organization of the avascular retina into a contracting scar.

(Arch Ophthalmol 95:217-223, 1977)