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Article
May 1977

The Conjunctival Sickling Sign, Hemoglobin S, and Irreversibly Sickled Erythrocytes

Author Affiliations

From the Sickle Cell Eye Clinic, University of Illinois Eye and Ear Infirmary, Chicago. Dr Asdourian is now with the Department of Ophthalmology, University of Massachusetts, Worcester; and Dr Goldbaum is with the Department of Ophthalmology, University of California at San Diego.

Arch Ophthalmol. 1977;95(5):808-811. doi:10.1001/archopht.1977.04450050086008
Abstract

• Sixty-five patients with hemoglobins AS, SC, and SS were investigated in a masked fashion. We observed a statistically significant positive correlation between the severity of conjunctival sickling signs and the counts of irreversibly sickled cells in each hemoglobinopathy group. We also observed a statistically significant positive correlation between the severity of the conjunctival vasculopathy and the percentage of sickle hemoglobin in the total group of patients with hemoglobins AS, SC, and SS.

(Arch Ophthalmol 95:808-811, 1977)

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