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June 1977

Quantitative Antibiotic Sensitivity Determinations of Staphylococcus aureus Isolated From Eye Cultures

Author Affiliations

From the Francis I. Proctor Foundation for Research in Ophthalmology and the Department of Ophthalmology, University of California, San Francisco. Dr Hong Bok Kim was a Cecilia Vaughan Memorial Fellow at the Proctor Foundation 1974-75. His present address is Yonsei University College of Medicine, Seoul.

Arch Ophthalmol. 1977;95(6):1065-1067. doi:10.1001/archopht.1977.04450060152016

• The sensitivities of 108 strains of Staphylococcus aureus, isolated from patients with a variety of ocular conditions, were tested quantitatively against nine antibiotics by means of a microtiter broth-dilution method. Of the nine antibiotics, cephalothin sodium had the lowest (and therefore the best) minimum bactericidal concentration (MBC) and minimum inhibitory concentration (MIC). The MBC and MIC of gentamicin sulfate were very close to those of cephalothin. The MBCs and MICs of erythromycin, ampicillin sodium, penicillin, tetracycline, methicillin sodium, and carbenicillin disodium Were moderately good. Chloramphenicol had the poorest response.

(Arch Ophthalmol 95:1065-1067, 1977)