October 1977

Anterior Uveitis in Juvenile Rheumatoid Arthritis

Author Affiliations

From the Medical Research Council Rheumatism Unit, Canadian Red Cross Memorial Hospital, Taplow, Berkshire, England.

Arch Ophthalmol. 1977;95(10):1794-1797. doi:10.1001/archopht.1977.04450100096010

• The ocular and systemic characteristics of 160 patients with anterior uveitis and seronegative juvenile rheumatoid arthritis are reviewed. Chronic uveitis occurred in 131 patients, 76% of whom were girls. Both eyes were involved in 70% of the cases. Band keratopathy occurred in 41% of the eyes, cataract in 42%, and secondary glaucoma in 19%. Only 11 patients had uveitis before the onset of arthritis. Notable correlations included a pauciarticular onset of arthritis in 95% of the patients, and positive tests for antinuclear antibody in 82%. Of 29 patients with acute anterior uveitis, 27 were boys. The inflammation responded well to therapy, and serious complications did not occur. At follow-up 21 patients had typical ankylosing spondylitis, and five had sacroiliitis. The incidence of positive results of tests for HLA-B27 antigen was 94%.

(Arch Ophthalmol 95:1794-1797, 1977)