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Article
November 1977

Optic Disc in GlaucomaTopography and Extent of Fluorescein Filling Defects

Author Affiliations

From the Department of Ophthalmology, New England Center and Tufts University School of Medicine, Boston. Dr Fishbein is now in private practice in Augusta, Ga.

Arch Ophthalmol. 1977;95(11):1975-1979. doi:10.1001/archopht.1977.04450110069003
Abstract

• The topography and extent of localized areas of hypofluorescence or absolute filling defects of the optic discs of glaucomatous patients correlated positively with the loss of visual field. Filling defects tended to cluster at the inferior and superior poles of the optic disc and were closer to the disc margin than to the center. The location of the defects corresponded with the expected site of visual field loss. There was a positive correlation between the percent area of the filling defects and the degree of visual field loss. These observations support the concept that fluorescein filling defects of the optic disc in glaucoma represent areas of ischemia that are highly correlated with loss of visual field.

(Arch Ophthalmol 95:1975-1979, 1977)

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