• Mild pigmentary changes found in the fundi of two patients with neurofibromatosis, resembled café-au-lait spots homologous with skin manifestations of the disease. In one, associated retinal hamartomas were present. The café-au-lait lesions were clinically distinct from previously reported uveal melanomas and may represent a hitherto unrecognized sign of ocular neurofibromatosis.
(Arch Ophthalmol 95:1990-1993, 1977)
Cotlier E. Café-au-Lait Spots of the Fundus in Neurofibromatosis. Arch Ophthalmol. 1977;95(11):1990-1992. doi:10.1001/archopht.1977.04450110084007