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To the Editor.–I write about the article entitled "Corneal Endothelial Changes with Long-Term Topical Epinephrine Therapy" by Waltman et al that appeared in the Archives (95:1357-1358, 1977). I believe that this article should have been entitled "Corneal Endothelial Count Asymmetries Associated With Long-Term Asymmetrical Topical Epinephrine Therapy." In no part of the report is there an endothelial cell count before epinephrine therapy and a subtraction of a later count from this to produce a difference which is what a change is. The concept is certainly worthy of further study but this article has not documented a change.
Joseph NH. Change Article Title. Arch Ophthalmol. 1977;95(12):2230. doi:10.1001/archopht.1977.04450120136022