• Eighty-six patients who underwent intraocular lens implantation in one eye, with no surgery in the contralateral eye, were examined by specular microscopy. The mean endothelial cell density (ECD) was 39.5% lower in the operated eye. The loss of ECD was roughly proportional to the endothelial trauma from the intraocular lens at the time of surgery.
Sugar J, Mitchelson J, Kraff M. Endothelial Trauma and Cell Loss From Intraocular Lens Insertion. Arch Ophthalmol. 1978;96(3):449-450. doi:10.1001/archopht.1978.03910050225006