• The term fibrous histiocytoma encompasses a heterogeneous group of tumors believed to have a common origin in the histiocyte. These tumors demonstrate a wide histopathologic spectrum ranging from a predominantly cellular to a predominantly fibrous pattern. No clinical or histological criteria have been identified that can predict malignant behavior. Although generally characterized by local recurrence, a metastatic potential does exist. Fibrous histiocytoma of the thigh metastasized to the orbit.
Stewart WB, Newman NM, Cavender JC, Spencer WH. Fibrous Histiocytoma Metastatic to the Orbit. Arch Ophthalmol. 1978;96(5):871-873. doi:10.1001/archopht.1978.03910050473016