• Patients with active dendritic herpetic keratitis that was unresponsive to topical idoxuridine or vidarabine therapy were treated topically with a 1% solution of trifluridine. The dendritic ulcers healed in an average time of 6.1 days. All patients tolerated the drug well except for one patient in whom a reversible crystalline epithelial keratitis developed.
Hyndiuk RA, Charlin RE, Alpren TVP. Trifluridine in Resistant Human Herpetic Keratitis. Arch Ophthalmol. 1978;96(10):1839-1841. doi:10.1001/archopht.1978.03910060351011