To the Editor.
—In the recent article on central retinal vein occlusion (CRVO) in the Archives (96:311-323, 1978), Hayreh and co-workers present further experimental data purporting to substantiate the hypothesis that an "ischemic capillaropathy" resulting from retinal arterial occlusion is an essential factor in the development of hemorrhages after CRVO. As our views were both criticized and misrepresented, we would like to make a few comments.We have recently performed similar experiments (D. McLeod, FRCS, E. M. Kohner, MD, FRCP, and J. Marshall, PhD, unpublished findings, 1978). We agree with Hayreh's recent observation that retinal hemorrhages, sometimes in profusion, can result from occlusion of the central retinal vein alone as it emerges from the optic nerve sheath of monkeys ("pure CRVO"). Our experimental model correlates reasonably well with the clinical picture of CRVO with hemorrhages.Whenever infarction of the inner retina is produced by central retinal artery occlusion (CRAO) and
McLeod D, Kohner EM. Hemorrhages After Central Retinal Vein Occlusion. Arch Ophthalmol. 1978;96(10):1921. doi:10.1001/archopht.1978.03910060407025