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January 1979

Bupivacaine Anesthesia in Retinal Detachment Surgery

Author Affiliations

From the Department of Ophthalmology, Washington University School of Medicine, St Louis. Dr Holekamp is now with the Department of Ophthalmology, University of South Florida, Tampa.

Arch Ophthalmol. 1979;97(1):109-111. doi:10.1001/archopht.1979.01020010049012

• Retinal detachment surgery and other long-duration ocular procedures can be performed safely with local anesthesia, but a long-acting anesthetic is required. A randomized and masked prospective series of 126 scleral buckling procedures was undertaken to test a mixture of bupivacaine (Marcaine), lidocaine (Xylocaine), and epinephrine against lidocaine and epinephrine.

The data collected show a conclusive superiority of the bupivacaine mixture in longevity of action and overall performance. Also, there was significantly less variability in the quality of anesthesia with the mixture than with lidocaine (P =.0015).