• Pathological details in the ocular fundus can be seen with increased contrast when appropriate monochromatic illumination is used instead of white light. This noninvasive technique enhances the visualization of structures and the detection of changes in the fundus. It facilitates the localization of pathological lesions in the chorioretinal layers, and in some cases permits their differential diagnosis. Monochromatic ophthalmoscopy and fundus photography of 290 eyes with a variety of pathological conditions were performed. The spectral ranges for optimal visualization of various lesions of the retina and choroid were defined. The usefulness of the technique and its advantages and limitations in relation to the present fundus diagnostic methods of color photography and fluorescein angiography were evaluated.
Ducrey NM, Delori FC, Gragoudas ES. Monochromatic Ophthalmoscopy and Fundus PhotographyII. The Pathological Fundus. Arch Ophthalmol. 1979;97(2):288-293. doi:10.1001/archopht.1979.01020010140009