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February 1979

Vitrectomy in Experimental UveitisI. Operative Technique in Rabbits

Author Affiliations

From the Department of Ophthalmology, University Hospitals, Iowa City. Dr Kaplan is now with The Medical College of Wisconsin, Milwaukee.

Arch Ophthalmol. 1979;97(2):331-335. doi:10.1001/archopht.1979.01020010177021

• The effect of vitrectomy on the severity and frequency of recurrent episodes of uveitis was studied in the rabbit model of protein-induced uveitis. Since the ciliary complex of the adult rabbit has distinctive anatomic features, the technical aspects of vitrectomy were first studied in the normal rabbit eye. We concluded that a lensectomy-vitrectomy could be best accomplished in the rabbit with the Peyman vitreophage through a transciliary body approach. Furthermore, postoperative inflammation was reduced by the preoperative administration of indomethacin (Indocin), as well as the use of Ringer's solution as the intraocular infusate.