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May 1979

Familial Corneal Hypesthesia

Author Affiliations

From the Department of Ophthalmology, St Louis University Medical Center and St Mary's Medical Center, St Louis (Dr Purcell), and the Department of Ophthalmology, University of Iowa Hospitals and Clinics, Iowa City (Dr Krachmer).

Arch Ophthalmol. 1979;97(5):872-874. doi:10.1001/archopht.1979.01020010430005

• A 4-year-old boy with severe, diffuse, asymptomatic, punctate, epithelial corneal erosions had bilateral sharply decreased corneal sensation with normal skin sensation in the distribution of the trigeminal nerves. Subsequent family studies disclosed five family members with similar corneal changes and decreased corneal sensation and no punctate erosions. None had decreased skin sensation in the distribution of the fifth cranial nerve. No environmental factors or evidence of local or systemic disease accounted for these findings.