• Thirty employees of an industrial plant involved in the manufacture of silver nitrate and silver oxide underwent ophthalmologic evaluation in an effort to evaluate the frequency and extent of ocular argyrosis. The most frequently noted ocular abnormality was pigmentation of the conjunctiva, present in 20 workers; corneal pigmentation occurred in 15 workers. A direct relationship existed between the levels of pigmentation and duration of employment. Ocular pigmentation was seen more frequently than cutaneous pigmentation. Ten workers noted decreased night vision, but electrophysiologic and psychophysiologic studies of seven of these ten workers demonstrated no functional deficits.
Moss AP, Sugar A, Hargett NA, Atkin A, Wolkstein M, Rosenman KD. The Ocular Manifestations and Functional Effects of Occupational Argyrosis. Arch Ophthalmol. 1979;97(5):906-908. doi:10.1001/archopht.1979.01020010464015