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Twenty-one years have elapsed since the publication of Dr Mohs' first book on chemosurgery. The main recent advancement in this area has been the fresh-tissue technique. This technique not only provides a more rapid excision of the tumor, but has less morbidity and provides the opportunity for immediate reconstruction. Dr Mohs shows his vast experience and reports his excellent results in 3,467 cases of basal cell carcinoma and 822 cases of squamous cell carcinoma managed with the fresh-tissue technique. The results are comparable to those in over 13,000 cases of skin cancer managed with the fixed-tissue technique.
Dr Mohs explains the technique of microscopically controlled excision in detail. He emphasizes the use of this excision for cancer for all areas of the skin including the face, scalp, neck, nose, ears, eyelids, extremities, and trunk. The unprecedented high cure rates, as well as the conservation of tissues provided by this technique,
Anderson R. Chemosurgery: Microscopically Controlled Surgery for Skin Cancer. Arch Ophthalmol. 1979;97(9):1769. doi:10.1001/archopht.1979.01020020297027