• A 15-year follow-up examination of a boy with Rieger's syndrome showed that the anterior segment changes in this disease may be slowly progressive in the absence of glaucoma or miotic treatment. The patient also had two recently recognized systemic features of the syndrome, umbilicus cutis and hypospadias.
Judisch GF, Phelps CD, Hanson J. Rieger's SyndromeA Case Report With a 15-Year Follow-up. Arch Ophthalmol. 1979;97(11):2120-2122. doi:10.1001/archopht.1979.01020020438004