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Article
February 1980

Juvenile Fibromatosis of the Periorbital Region and EyelidA Clinicopathologic Study of Six Cases

Author Affiliations

From the Registry of Ophthalmic Pathology, Armed Forces Institute of Pathology, Washington, DC.

Arch Ophthalmol. 1980;98(2):280-285. doi:10.1001/archopht.1980.01020030276007
Abstract

• Six cases of juvenile fibromatosis of the periorbital region and eyelid were studied. The median age of the patients was 8 years (range, 1 to 11 years). A definite propensity for involvement of the infraorbital region and lower eyelid was observed. Three tumors exhibited a prominent lobular pattern and were adherent to the periosteum. The main entities in the differential diagnosis included leiomyoma, neurofibroma, and well-differentiated fibrosarcoma. Two of six tumors recurred locally but did not metastasize. Electron microscopic studies disclosed that the spindle-shaped tumor cells exhibited features of fibroblasts. It appears that conservative treatment (ie, local excision) is adequate.

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