• The eyes of a 53-year-old woman with K light chain macroglobulinemia were studied histopathologically. Retinal hemorrhages were observed on gross examination. Microscopic examination disclosed eosinophilic, PAS-positive deposits in cystoid spaces within the outer plexiform layer, in the inner retina, and about photoreceptors. Immunofluorescent studies showed that the deposits contained IgM. Aneurysmal dilations of small retinal vessels were demonstrated as well.
Friedman AH, Marchevsky A, Odel JG, Gerber MA, Thung SN. Immunofluorescent Studies of the Eye in Waldenström's Macroglobulinemia. Arch Ophthalmol. 1980;98(4):743-746. doi:10.1001/archopht.1980.01020030737020