• One of two cases of endogenous Aspergillus endophthalmitis in abusers of intravenously administered drugs was treated successfully by subtotal pars plana vitrectomy; amphotericin B administered by intravitreal, periocular, and systemic routes; and flucytosine administered systemically. Aspergillus sp should be considered a possible pathogenic organism in drug abusers with endogenous endophthalmitis. An aggressive diagnostic and therapeutic approach may result in preservation of useful vision.
Doft BH, Clarkson JG, Rebell G, Forster RK. Endogenous Aspergillus Endophthalmitis in Drug Abusers. Arch Ophthalmol. 1980;98(5):859-862. doi:10.1001/archopht.1980.01020030853010