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Article
August 1980

B-K Mole SyndromeCutaneous and Ocular Malignant Melanoma

Author Affiliations

From the Department of Ophthalmology, the New York Hospital-Cornell Medical Center, the Manhattan Eye, Ear, and Throat Hospital, New York.

Arch Ophthalmol. 1980;98(8):1397-1399. doi:10.1001/archopht.1980.01020040249006
Abstract

• A 51-year-old white man had the B-K mole syndrome (multiple large atypical cutaneous nevi of the upper part of the trunk and extremities, inherited as an autosomal dominant trait, and thought to be more susceptible to malignant transformation), so named after two patients in whom the syndrome was first observed. Two cutaneous malignant melanomas (thigh and back) and an ocular malignant melanoma (ciliary body and iris) simultaneously developed. Patients with B-K mole syndrome have been known to have a very high risk for the development of cutaneous melanoma (including multiple primary cutaneous melanomas) and multiple primary malignancies. There may be a propensity in these patients for development of ocular melanomas.

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