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October 1980

Bright-Flash Electroretinography and Vitreous HemorrhageAn Experimental Study in Primates

Author Affiliations

From the Estelle Doheny Eye Foundation and the Department of Ophthalmology, University of Southern California School of Medicine, Los Angeles.

Arch Ophthalmol. 1980;98(10):1823-1828. doi:10.1001/archopht.1980.01020040675017

• Serial, bright-flash electroretinograms (ERGs) were recorded from rhesus monkey eyes before and after a standard posterior penetrating ocular injury and injection of 0.5 mL of blood into the vitreous. This procedure resulted in a progressive depression to virtual nonrecordability of the ERG during a period of several weeks, owing to a combined progressive increase in optical density and loss of retinal function. The ERG depression, however, was reversible, showing a remarkable recovery during the subsequent four to eight weeks. These findings suggest that in the presence of a recent, massive vitreous hemorrhage, a nonrecordable bright-flash ERG does not necessarily indicate a permanent loss of retinal function.