• Uncontrolled unilateral glaucoma developed in the right eye of a 24-year-old woman. It was caused by the diffuse growth of a nonpigmented nevus of the iris into the anterior chamber angle. Histologically, the nonpigmented nevus cells in the angle were distinguishable from a proliferation of corneal endothelium. Clinically, there was no heterochromia, and a tumor was not suspected as the cause of the glaucoma.
Nik NA, Hidayat A, Zimmerman LE, Fine BS. Diffuse Iris Nevus Manifested by Unilateral Open Angle Glaucoma. Arch Ophthalmol. 1981;99(1):125-127. doi:10.1001/archopht.1981.03930010127017