• Primary herpes simplex infection may involve the lining of the lacrimal canaliculi and result in permanent strictures and epiphora. Five cases are reported and analyzed in combination with previously reported cases. Antiviral medication was not responsible for lacrimal drainage obstruction in these cases.
Harris GJ, Hyndiuk RA, Fox MJ, Taugher PJ. Herpetic Canalicular Obstruction. Arch Ophthalmol. 1981;99(2):282-283. doi:10.1001/archopht.1981.03930010284012