• A 35-year-old man demonstrated sulfisoxazole diolamine-induced photosensitivity during treatment for staphylococcal blepharitis. This reaction was easily avoided by applying the ointment at bedtime and covering the eyelids during sunbathing while in therapy. A drug-induced photosensitivity reaction should be considered in cases of staphylococcal blepharitis resistant to or aggravated by eyelid-margin therapy with sulfonamides.
Flach A. Photosensitivity to Sulfisoxazole Ointment. Arch Ophthalmol. 1981;99(4):609-610. doi:10.1001/archopht.1981.03930010609004