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—Concerning the response of Dr Radius to our article, we have noted that in patients with ocular hypertension, the rate of fluorescein filling of the retinal arteries during the fluorescein angiograms is less than in normal subjects. Also, the retinal arteries of glaucomatous eyes took a longer time to fill with fluorescein than normal eyes, as measured by peak time minus first appearance time of the fluorescein in the retinal arteries.We suggested that this indicated a deficit in autoregulation of the retinal arterial circulation related to increased IOP. Radius is correct in that we did not measure volume of blood volume flow through the retinal arterial circulation, which we had indicated in our article. Therefore, we do not mean to imply that autoregulation defined as flow in relation to volume of blood could be impaired. However, since we did observe a decrease in the rate of filling
Schwartz B. Fluorescein Angiography in Eyes With Elevated Intraocular Pressure-Reply. Arch Ophthalmol. 1981;99(4):698. doi:10.1001/archopht.1981.03930010698027