• Electrophysiologic studies were performed on 17 patients with bilateral optic nerve hypoplasia. Since most patients were infants, the diffuse light visualevoked response was more helpful than the visual-evoked response obtained with pattern stimulation. In children over 1 year of age, the amplitude with diffuse light stimulation correlated well with other clinical measurements used to assess visual function. Before 6 months of age, it correlated better with visual prognosis than did clinical analysis. Photopic and scotopic electroretinographic measurements were normal in all except two in whom the scotopic b wave was supernormal.
Sprague JB, Wilson WB. Electrophysiologic Findings in Bilateral Optic Nerve Hypoplasia. Arch Ophthalmol. 1981;99(6):1028-1029. doi:10.1001/archopht.1981.03930011028009