• The combination of unilateral proliferative diabetic retinopathy (PDR) in one eye and nonproliferative diabetic retinopathy (NPDR) in the fellow eye was observed in 10.1% of patients with PDR. Most patients were between the ages of 50 and 70 years; the majority had adultonset diabetes mellitus. Unilateral aphakia and anisometropia of greater than 1 diopter were both infrequently seen. The incidence of glaucoma was unremarkable. Unilateral elevated—but not necessarily abnormal—intraocular pressure was found in a significantly larger proportion of eyes with NPDR (20%) than with PDR (12%). Most patients had moderate to severe angiopathy or exudation in the eye with NPDR and modest PDR in the fellow eye; however, one third had moderate to severe PDR. In only 2% of the patients was visual acuity less than 20/200 on initial examination.
Valone JA, McMeel JW, Franks EP. Unilateral Proliferative Diabetic RetinopathyI. Initial Findings. Arch Ophthalmol. 1981;99(8):1357-1361. doi:10.1001/archopht.1981.03930020231002