• Polymethylmethacrylate lenses with nylon loops activate complement in normal human serum and provoke generation of C5-derived peptides with chemotactic activity for polymorphonuclear leukocytes. These observations may explain one aspect of the pathway of implantinduced inflammation and its clinical consequences.
Galin MA, Goldstein IM, Tuberville A, Perez HD, Kaplan H. Intraocular Lenses Generate Chemotactic Activity in Human SerumBinkhorst Lecture Part III. Arch Ophthalmol. 1981;99(8):1434-1435. doi:10.1001/archopht.1981.03930020308023