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September 1981

Successful Treatment of Candida albicans Endophthalmitis With Intravitreal Amphotericin B

Author Affiliations

From the Department of Ophthalmology, Washington Hospital Center and George Washington University School of Medicine, Washington, DC.

Arch Ophthalmol. 1981;99(9):1565-1567. doi:10.1001/archopht.1981.03930020439006

• A severely debilitated 38-year-old woman had culture-proved Candida albicans endophthalmitis that resolved after treatment with a single intravitreal injection of 5 μg of amphotericin B and a total of only 190 mg of intravenous amphotericin B. The patient recovered visual acuity of 6/7.5 (20/25), and her electroretinogram was normal 22 months after operation. There was no evidence of a retinal toxic reaction to amphotericin B on long-term follow-up.