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September 1981

Prognostic Indicators of Herpetic KeratitisAnalysis of a Five-Year Observation Period After Corneal Ulceration

Author Affiliations

From the Departments of Clinical Ophthalmology (Drs Wilhelmus, Coster, and Falcon) and Preventive Ophthalmology (Dr Jones), Moorfields Eye Hospital; and the Computer Section (Mr Donovan), Institute of Ophthalmology, London. Dr Coster is now with The Flinders University of South Australia, Adelaide.

Arch Ophthalmol. 1981;99(9):1578-1582. doi:10.1001/archopht.1981.03930020452009

• Clinical features of 152 patients with herpetic keratitis after a five-year observation period were analyzed. When compared with dendritic ulceration, geographic ulcers that had been symptomatically present for a longer time were more likely to have been treated with a topical steroid and took longer to heal. After treatment of the corneal ulceration, 40% of the patients experienced a recurrent herpetic ulcer, 25% experienced disciform or irregular stromal keratouveitis, 5% experienced ocular hypertension, and 6% had a decrease in visual acuity caused by corneal scarring. Recurrent ulcerative herpetic keratitis occurred more frequently in men and in patients who entered the study with a history of previous herpetic ulceration.