• Fifteen white patients and three black patients with Stevens-Johnson syndrome (SJS) with ocular involvement had HLA typing performed. The HLA-Bw44 antigen was found to have an increased frequency of 66.7% in white patients with SJS with ocular involvement, which was statistically significant when compared with a frequency of 20.4% in the white control population. The results of this study suggest that there is an immunogenetic susceptibility to the development of SJS with ocular manifestations in white patients.
Mondino BJ, Brown SI, Biglan AW. HLA Antigens in Stevens-Johnson Syndrome With Ocular Involvement. Arch Ophthalmol. 1982;100(9):1453-1454. doi:10.1001/archopht.1982.01030040431012