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Article
December 1982

Bilateral Acute Retinal NecrosisClinical and Ultrastructural Study

Author Affiliations

From the Department of Retina Research, Eye Research Institute of the Retina Foundation and Retina Associates, Boston (Drs Topilow, Nussbaum, and Freeman), and the Department of Pathology, Harvard Medical School and the James Homer-Wright Laboratories, Massachusetts General Hospital, Boston (Drs Dickersin and Szyfelbein).

Arch Ophthalmol. 1982;100(12):1901-1908. doi:10.1001/archopht.1982.01030040881002
Abstract

• In a 28-year-old man with bilateral acute retinal necrosis, a severe, bilateral panuveitis, necrotizing retinitis, and retinal vasculitis developed. Severe vitreous traction on atrophic retina resulted in bilateral giant retinal tears with an inoperable retinal detachment in the right eye. A retinal detachment developed in the left eye that was reattached after a pars plana vitrectomy and two scleral buckling procedures, but ultimately became inoperable. Large numbers of lymphocytes in the vitreous aspirate and depressed serum complement levels may indicate that an immune mechanism was involved in the necrotizing retinitis. We present the first electron microscopic evidence, to our knowledge, that preretinal membranes occurring in rhegmatogenous retinal detachment due to bilateral acute retinal necrosis arise from retinal pigment epithelium.

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