• Five patients had a bilateral hereditary ocular syndrome composed of posterior microphthalmos with a papillomacular fold and high hyperopia. Anterior segment dimensions were near normal; the vitreous compartment was markedly foreshortened. A papillomacular retinal fold extending from the center of the fovea toward the optic nerve head was present. Visual acuity ranged from 0.05 (20/400) to 0.6 (20/33); refractive errors ranged from +11.25 to +17.50 diopters. An autosomal recessive pattern of inheritance is postulated.
Spitznas M, Gerke E, Bateman JB. Hereditary Posterior Microphthalmos With Papillomacular Fold and High Hyperopia. Arch Ophthalmol. 1983;101(3):413-417. doi:10.1001/archopht.1983.01040010413014